Sasaki Y et al, Administration of biotin prevents the development of insulin resistance in the skeletal muscles of Otsuka Long-Evans Tokushima Fatty rats. Food Funct. 2012 Apr;3(4):414-9.
Coggeshall JC, Heggers JP, Robson MC, et al. Biotin status and plasma glucose in diabetics. Ann N Y Acad Sci 1985;447:389-92.
Zhang H et al, A high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus, J Nutr Sci Vitaminol (Tokyo). 1996 Dec;42(6):517-26
Larrieta E et al, A high biotin diet improves the impaired glucose tolerance of long-term spontaneously hyperglycemic rats with non-insulin-dependent diabetes mellitus, Eur J Pharmacol. 2010 Oct 10;644(1-3):263-8
Koutsikos D et al, Biotin for diabetic peripheral neuropathy. Biomed Pharmacother 1990;44(10):511-4.
Maebashi M, et al. Therapeutic evaluation of the effect of biotin on hyperglycemia in patients with non-insulin dependent diabetes mellitus. J Clin Biochem Nutr. 1993;14:211-218.
Singer GM, et al. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43.
Revilla-Monsalve C et al, Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia, Biomed Pharmacother. 2006 May;60(4):182-5.
Geohas J et al, Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial, Am J Med Sci. 2007 Mar;333(3):145-53
Camacho FM, et al. Zinc aspartate, biotin, and clobetasol propionate in the treatment of alopecia areata in childhood. Pediatr Dermatol 1999;16:336-8.
Hochman LG et al, Brittle nails: response to daily biotin supplementation. Cutis. 1993;51(4):303-305
Mock DM, Marginal biotin deficiency is common in normal human pregnancy and is highly teratogenic in mice., J Nutr. 2009 Jan;139(1):154-7
Zempleni J et al, Marginal biotin deficiency is teratogenic., Proc Soc Exp Biol Med. 2000 Jan;223(1):14-21
Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000
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