Distribution : Following intravenous administration of 1 mg of fluticasone propionate in healthy volunteers, the initial disposition phase for fluticasone propionate was rapid and consistent with its high lipid solubility and tissue binding. The apparent volume of distribution averaged L/kg (range, - L/kg). The percentage of fluticasone propionate bound to human plasma proteins averaged 91%. Fluticasone propionate is weakly and reversibly bound to erythrocytes. Fluticasone propionate is not significantly bound to human transcortin.
Overdose Symptoms of overdose strofantinom-T varied. Cardio-vascular system: arrhythmia, including bradycardia, AV-block, ventricular tachycardia or extrasystole, ventricular fibrillation. On the part of the digestive tract: anorexia, nausea, vomiting, diarrhea. On the part of the central nervous system and sensory organs: headache , fatigue. dizziness, rarely – staining the surrounding objects in green and yellow colors, a sense of flicker flies before his eyes, blurred vision, scotoma, macro- and micropsia: very rarely confusion, sinkoialnye state. With the development of glycoside intoxication drug buy testosterone propionate should be discontinued; assign the patient potassium supplements, parenteral administration unitiola, symptomatic therapy.